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HDAC6 and ERK/ADAM17 Regulate VEGF-Induced NOTCH Signaling in Lung Endothelial Cells

Angiogenesis plays a critical role in various physiological and pathological processes and is regulated by VEGF. Histone Deacetylase 6 (HDAC6) is a class IIB HDAC that regulates cytoplasmic signaling through deacetylation and is emerging as a target for modulating angiogenesis. We investigated the h...

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Detalles Bibliográficos
Autores principales: Xia, Sheng, Menden, Heather L., Mabry, Sherry M., Sampath, Venkatesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526732/
https://www.ncbi.nlm.nih.gov/pubmed/37759454
http://dx.doi.org/10.3390/cells12182231