Anti-Cancer Potential of Transiently Transfected HER2-Specific Human Mixed CAR-T and NK Cell Populations in Experimental Models: Initial Studies on Fucosylated Chondroitin Sulfate Usage for Safer Treatment

Human epidermal growth factor receptor 2 (HER2) is overexpressed in numerous cancer cell types. Therapeutic antibodies and chimeric antigen receptors (CARs) against HER2 were developed to treat human tumors. The major limitation of anti-HER2 CAR-T lymphocyte therapy is attributable to the low HER2 e...

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Detalles Bibliográficos
Autores principales: Chikileva, Irina O., Bruter, Alexandra V., Persiyantseva, Nadezhda A., Zamkova, Maria A., Vlasenko, Raimonda Ya., Dolzhikova, Yuliya I., Shubina, Irina Zh., Donenko, Fedor V., Lebedinskaya, Olga V., Sokolova, Darina V., Pokrovsky, Vadim S., Fedorova, Polina O., Ustyuzhanina, Nadezhda E., Anisimova, Natalia Yu., Nifantiev, Nikolay E., Kiselevskiy, Mikhail V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526813/
https://www.ncbi.nlm.nih.gov/pubmed/37761005
http://dx.doi.org/10.3390/biomedicines11092563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526813/
https://www.ncbi.nlm.nih.gov/pubmed/37761005
http://dx.doi.org/10.3390/biomedicines11092563

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