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Inhibition of Anaplastic Lymphoma Kinase (Alk) as Therapeutic Target to Improve Brain Function in Neurofibromatosis Type 1 (Nf1)

SIMPLE SUMMARY: Neurofibromatosis type 1 (Nf1) is a genetically determined neurodevelopmental disorder and tumor syndrome with an incidence of approximately 1/3000 live births. It is caused by loss of function mutations in the neurofibromin gene (Nf1) and is estimated to affect 100,000 people in the...

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Detalles Bibliográficos
Autores principales: Weiss, Joseph B., Raber, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526845/
https://www.ncbi.nlm.nih.gov/pubmed/37760547
http://dx.doi.org/10.3390/cancers15184579