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GMP Synthetase: Allostery, Structure, and Function

Glutamine amidotransferases (GATs) catalyze the hydrolysis of glutamine and transfer the generated ammonia to diverse metabolites. The two catalytic activities, glutaminolysis and the subsequent amination of the acceptor substrate, happen in two distinct catalytic pockets connected by a channel that...

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Detalles Bibliográficos
Autores principales: Ballut, Lionel, Violot, Sébastien, Kumar, Sanjeev, Aghajari, Nushin, Balaram, Hemalatha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526850/
https://www.ncbi.nlm.nih.gov/pubmed/37759779
http://dx.doi.org/10.3390/biom13091379