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Tumor-Promoting Role of GNA14 in Colon Cancer Development

SIMPLE SUMMARY: In this study, we showed that knockdown of GNA14 gene, which encodes one of the α subunits of G-protein, inhibits the proliferation of colorectal cancer (CRC) cells harboring truncated APC mutations, and that Gna14 deletion in Apc(Min/+) mice attenuates intestinal carcinogenesis thro...

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Detalles Bibliográficos
Autores principales: Park, Rahui, Lee, Seungmin, Chin, Hyunjung, Nguyen, Anh Thai-Quynh, Lee, Daekee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527020/
https://www.ncbi.nlm.nih.gov/pubmed/37760541
http://dx.doi.org/10.3390/cancers15184572