Transcriptomic Analysis in the Hippocampus and Retina of Tg2576 AD Mice Reveals Defective Mitochondrial Oxidative Phosphorylation and Recovery by Tau 12A12mAb Treatment

Increasing evidence implicates decreased energy metabolism and mitochondrial dysfunctions among the earliest pathogenic events of Alzheimer’s disease (AD). However, the molecular mechanisms underlying bioenergetic dysfunctions in AD remain, to date, largely unknown. In this work, we analyzed transcr...

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Detalles Bibliográficos
Autores principales: Morello, Giovanna, Guarnaccia, Maria, La Cognata, Valentina, Latina, Valentina, Calissano, Pietro, Amadoro, Giuseppina, Cavallaro, Sebastiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527038/
https://www.ncbi.nlm.nih.gov/pubmed/37759477
http://dx.doi.org/10.3390/cells12182254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527038/
https://www.ncbi.nlm.nih.gov/pubmed/37759477
http://dx.doi.org/10.3390/cells12182254

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