X-ray Crystallographic Study of Preferred Spacing by the NF-κB p50 Homodimer on κB DNA

Though originally characterized as an inactive or transcriptionally repressive factor, the NF-κB p50 homodimer has become appreciated as a physiologically relevant driver of specific target gene expression. By virtue of its low affinity for cytoplasmic IκB protein inhibitors, p50 accumulates in the...

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Detalles Bibliográficos
Autores principales: Zhu, Norman, Mealka, Matthew, Mitchel, Shane, Milani, Christy, Acuña, Lisa M., Rogers, Eric, Lahana, Ashlee N., Huxford, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527052/
https://www.ncbi.nlm.nih.gov/pubmed/37759710
http://dx.doi.org/10.3390/biom13091310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527052/
https://www.ncbi.nlm.nih.gov/pubmed/37759710
http://dx.doi.org/10.3390/biom13091310

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