Feasibility and Activity of Megestrol Acetate in Addition to Etoposide, Doxorubicin, Cisplatin, and Mitotane as First-Line Therapy in Patients with Metastatic/Unresectable Adrenocortical Carcinoma with Low Performance Status

SIMPLE SUMMARY: Preclinical studies have shown an anti-neoplastic effect of progestins against adrenal cortical carcinoma. Progestins have a positive effect on patient cenesthesia and may make standard chemotherapy more tolerable. In this study, the addition of megestrol acetate to the etoposide, do...

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Detalles Bibliográficos
Autores principales: Turla, Antonella, Laganà, Marta, Abate, Andrea, Cremaschi, Valentina, Zamparini, Manuel, Chittò, Matteo, Consoli, Francesca, Alberti, Andrea, Ambrosini, Roberta, Tamburello, Mariangela, Grisanti, Salvatore, Tiberio, Guido Alberto Massimo, Sigala, Sandra, Cosentini, Deborah, Berruti, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527072/
https://www.ncbi.nlm.nih.gov/pubmed/37760461
http://dx.doi.org/10.3390/cancers15184491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527072/
https://www.ncbi.nlm.nih.gov/pubmed/37760461
http://dx.doi.org/10.3390/cancers15184491

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