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Feasibility and Activity of Megestrol Acetate in Addition to Etoposide, Doxorubicin, Cisplatin, and Mitotane as First-Line Therapy in Patients with Metastatic/Unresectable Adrenocortical Carcinoma with Low Performance Status
SIMPLE SUMMARY: Preclinical studies have shown an anti-neoplastic effect of progestins against adrenal cortical carcinoma. Progestins have a positive effect on patient cenesthesia and may make standard chemotherapy more tolerable. In this study, the addition of megestrol acetate to the etoposide, do...
Autores principales: | Turla, Antonella, Laganà, Marta, Abate, Andrea, Cremaschi, Valentina, Zamparini, Manuel, Chittò, Matteo, Consoli, Francesca, Alberti, Andrea, Ambrosini, Roberta, Tamburello, Mariangela, Grisanti, Salvatore, Tiberio, Guido Alberto Massimo, Sigala, Sandra, Cosentini, Deborah, Berruti, Alfredo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527072/ https://www.ncbi.nlm.nih.gov/pubmed/37760461 http://dx.doi.org/10.3390/cancers15184491 |
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