Design of a chimeric glycosyltransferase OleD for the site‐specific O‐monoglycosylation of 3‐hydroxypyridine in nosiheptide

To identify the potential role of the 3‐hydroxyl group of the pyridine ring in nosiheptide (NOS) for its antibacterial activity against Gram‐positive pathogens, enzymatic glycosylation was utilized to regio‐selectively create a monoglycosyl NOS derivative, NOS‐G. For this purpose, we selected OleD,...

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Detalles Bibliográficos
Autores principales: Zhao, Ling, Xu, Yuncong, Chen, Manting, Wu, Lingrui, Li, Meng, Lu, Yuanyuan, Lu, Meiling, Chen, Yijun, Wu, Xuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527214/
https://www.ncbi.nlm.nih.gov/pubmed/37606280
http://dx.doi.org/10.1111/1751-7915.14332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527214/
https://www.ncbi.nlm.nih.gov/pubmed/37606280
http://dx.doi.org/10.1111/1751-7915.14332

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