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Design of a chimeric glycosyltransferase OleD for the site‐specific O‐monoglycosylation of 3‐hydroxypyridine in nosiheptide
To identify the potential role of the 3‐hydroxyl group of the pyridine ring in nosiheptide (NOS) for its antibacterial activity against Gram‐positive pathogens, enzymatic glycosylation was utilized to regio‐selectively create a monoglycosyl NOS derivative, NOS‐G. For this purpose, we selected OleD,...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527214/ https://www.ncbi.nlm.nih.gov/pubmed/37606280 http://dx.doi.org/10.1111/1751-7915.14332 |