Inhibition of EphA3 Expression in Tumour Stromal Cells Suppresses Tumour Growth and Progression

SIMPLE SUMMARY: We have identified the cell guidance receptor EphA3 on distinct stromal/fibroblast-like cell types in the tumour microenvironment (TME) that promote growth and angiogenesis, both in human cancers and in mouse tumour models. To investigate its role in the TME, we developed novel trans...

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Detalles Bibliográficos
Autores principales: Vail, Mary E., Farnsworth, Rae H., Hii, Linda, Allen, Stacey, Arora, Sakshi, Anderson, Robin L., Dickins, Ross A., Orimo, Akira, Wu, Sunny Z., Swarbrick, Alexander, Scott, Andrew M., Janes, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527215/
https://www.ncbi.nlm.nih.gov/pubmed/37760615
http://dx.doi.org/10.3390/cancers15184646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527215/
https://www.ncbi.nlm.nih.gov/pubmed/37760615
http://dx.doi.org/10.3390/cancers15184646

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