Syringin Prevents 6-Hydroxydopamine Neurotoxicity by Mediating the MiR-34a/SIRT1/Beclin-1 Pathway and Activating Autophagy in SH-SY5Y Cells and the Caenorhabditis elegans Model

Defective autophagy is one of the cellular hallmarks of Parkinson’s disease (PD). Therefore, a therapeutic strategy could be a modest enhancement of autophagic activity in dopamine (DA) neurons to deal with the clearance of damaged mitochondria and abnormal protein aggregates. Syringin (SRG) is a ph...

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Detalles Bibliográficos
Autores principales: Fu, Ru-Huei, Hong, Syuan-Yu, Chen, Hui-Jye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527269/
https://www.ncbi.nlm.nih.gov/pubmed/37759532
http://dx.doi.org/10.3390/cells12182310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527269/
https://www.ncbi.nlm.nih.gov/pubmed/37759532
http://dx.doi.org/10.3390/cells12182310

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