Cargando…

Syringin Prevents 6-Hydroxydopamine Neurotoxicity by Mediating the MiR-34a/SIRT1/Beclin-1 Pathway and Activating Autophagy in SH-SY5Y Cells and the Caenorhabditis elegans Model

Defective autophagy is one of the cellular hallmarks of Parkinson’s disease (PD). Therefore, a therapeutic strategy could be a modest enhancement of autophagic activity in dopamine (DA) neurons to deal with the clearance of damaged mitochondria and abnormal protein aggregates. Syringin (SRG) is a ph...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fu, Ru-Huei, Hong, Syuan-Yu, Chen, Hui-Jye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527269/ https://www.ncbi.nlm.nih.gov/pubmed/37759532 http://dx.doi.org/10.3390/cells12182310

Ejemplares similares

Ghrelin alleviates 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells
por: He, Xin, et al.
Publicado: (2021)

Astragalus Polysaccharide Suppresses 6-Hydroxydopamine-Induced Neurotoxicity in Caenorhabditis elegans
por: Li, Haifeng, et al.
Publicado: (2016)

Maackiain Ameliorates 6-Hydroxydopamine and SNCA Pathologies by Modulating the PINK1/Parkin Pathway in Models of Parkinson’s Disease in Caenorhabditis elegans and the SH-SY5Y Cell Line
por: Tsai, Rong-Tzong, et al.
Publicado: (2020)

Sinapic Acid Protects SH-SY5Y Human Neuroblastoma Cells against 6-Hydroxydopamine-Induced Neurotoxicity
por: Tungalag, Tsendsuren, et al.
Publicado: (2021)

Evaluation of 6-Hydroxydopamine and Rotenone In Vitro Neurotoxicity on Differentiated SH-SY5Y Cells Using Applied Computational Statistics
por: Simões, Rui F., et al.
Publicado: (2022)

7,8,4′-Trihydroxyisoflavone, a Metabolized Product of Daidzein, Attenuates 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells
por: Ko, Yong-Hyun, et al.
Publicado: (2019)

Lipid Analysis of the 6-Hydroxydopamine-Treated SH-SY5Y Cell Model for Parkinson’s Disease
por: Xicoy, Helena, et al.
Publicado: (2019)

Pharmacognostical Analysis and Protective Effect of Standardized Extract and Rizonic Acid from Erythrina velutina against 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells
por: Silva, Aline H., et al.
Publicado: (2016)

Protective effect of theaflavins on neuron against 6-hydroxydopamine-induced apoptosis in SH-SY5Y cells
por: Luo, Zihua, et al.
Publicado: (2012)

Protective effect of Artemisia absinthium on 6-hydroxydopamine-induced toxicity in SH-SY5Y cell line
por: Rashidi, Roghayeh, et al.
Publicado: (2021)

Teaghrelin Protects SH-SY5Y Cells against MPP(+)-Induced Neurotoxicity through Activation of AMPK/SIRT1/PGC-1α and ERK1/2 Pathways
por: Jhuo, Cian-Fen, et al.
Publicado: (2020)

Wnt3a protects SH-SY5Y cells against 6-hydroxydopamine toxicity by restoration of mitochondria function
por: Wei, Lei, et al.
Publicado: (2015)

Nitroxide Radical-Containing Redox Nanoparticles Protect Neuroblastoma SH-SY5Y Cells against 6-Hydroxydopamine Toxicity
por: Pichla, Monika, et al.
Publicado: (2020)

Emodin inhibits zinc-induced neurotoxicity in neuroblastoma SH-SY5Y cells
por: Liu, Wenzhou, et al.
Publicado: (2019)

Assessment of Neurotoxic Effects of Oxycodone and Naloxone in SH-SY5Y Cell Line
por: Lima, Luíza Siqueira, et al.
Publicado: (2023)

Ndfip1 Prevents Rotenone-Induced Neurotoxicity and Upregulation of α-Synuclein in SH-SY5Y Cells
por: Liu, Xin, et al.
Publicado: (2021)

Protective Effects of Jujubosides on 6-OHDA-Induced Neurotoxicity in SH-SY5Y and SK-N-SH Cells
por: Chen, Chao-Hsuan, et al.
Publicado: (2022)

Lithium protects against paraquat neurotoxicity by NRF2 activation and miR-34a inhibition in SH-SY5Y cells
por: Alural, Begum, et al.
Publicado: (2015)

Punicalagin Exerts Beneficial Functions in 6-Hydroxydopamine-Treated SH-SY5Y Cells by Attenuating Mitochondrial Dysfunction and Inflammatory Responses
por: Chu, Jianfeng, et al.
Publicado: (2018)

Carnosic Acid Alleviates Levodopa-Induced Dyskinesia and Cell Death in 6-Hydroxydopamine-lesioned Rats and in SH-SY5Y Cells
por: Lai, Chun-Yi, et al.
Publicado: (2021)

Syringin exerts anti‐inflammatory and antioxidant effects by regulating SIRT1 signaling in rat and cell models of acute myocardial infarction
por: Zhao, Di, et al.
Publicado: (2023)

Nec-1 Attenuates Neurotoxicity Induced by Titanium Dioxide Nanomaterials on Sh-Sy5y Cells Through RIP1
por: Zhou, Ting, et al.
Publicado: (2020)

Insulin Blocks Glutamate-Induced Neurotoxicity in Differentiated SH-SY5Y Neuronal Cells
por: Nampoothiri, Madhavan, et al.
Publicado: (2014)

Neurotoxicity Induced by Bupivacaine via T-Type Calcium Channels in SH-SY5Y Cells
por: Wen, Xianjie, et al.
Publicado: (2013)

Melamine Exacerbates Neurotoxicity in D-Galactose-Induced Neuronal SH-SY5Y Cells
por: Goyal, Juhi, et al.
Publicado: (2023)

Roles of receptor‐interacting protein kinase 1 in SH‐SY5Y cells with beta amyloid‐induced neurotoxicity
por: Chan, Hong‐Hao, et al.
Publicado: (2022)

Chikusetsu Saponin V Attenuates MPP(+)-Induced Neurotoxicity in SH-SY5Y Cells via Regulation of Sirt1/Mn-SOD and GRP78/Caspase-12 Pathways
por: Yuan, Ding, et al.
Publicado: (2014)

The 1-Tosylpentan-3-one Protects against 6-Hydroxydopamine-Induced Neurotoxicity
por: Kao, Chien-Jen, et al.
Publicado: (2017)

Retraction: Neurotoxicity Induced by Bupivacaine via T-Type Calcium Channels in SH-SY5Y Cells
Publicado: (2020)

Insights into cisplatin-induced neurotoxicity and mitochondrial dysfunction in Caenorhabditis elegans
por: Martínez-Fernández, Carmen, et al.
Publicado: (2022)

Caenorhabditis elegans as a Model to Study Manganese-Induced Neurotoxicity
por: Martins, Airton C., et al.
Publicado: (2022)

Baicalein Prevents 6-Hydroxydopamine-Induced Mitochondrial Dysfunction in SH-SY5Y Cells via Inhibition of Mitochondrial Oxidation and Up-Regulation of DJ-1 Protein Expression
por: Wang, Yue-Hua, et al.
Publicado: (2013)

Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop
por: Tang, Hengfang, et al.
Publicado: (2022)

Genetic Defects in Mitochondrial Dynamics in Caenorhabditis elegans Impact Ultraviolet C Radiation- and 6-hydroxydopamine-Induced Neurodegeneration
por: Hartman, Jessica H., et al.
Publicado: (2019)

N-Acetylcysteine in Combination with IGF-1 Enhances Neuroprotection against Proteasome Dysfunction-Induced Neurotoxicity in SH-SY5Y Cells
por: Cheng, Benxu, et al.
Publicado: (2016)

AMBRA1-Mediated Mitophagy Counteracts Oxidative Stress and Apoptosis Induced by Neurotoxicity in Human Neuroblastoma SH-SY5Y Cells
por: Di Rita, Anthea, et al.
Publicado: (2018)

In Ovo and In Silico Evaluation of the Anti-Angiogenic Potential of Syringin
por: Aventurado, Charlaine A, et al.
Publicado: (2020)

Involvement of Mu Opioid Receptor Signaling in the Protective Effect of Opioid against 6-Hydroxydopamine-Induced SH-SY5Y Human Neuroblastoma Cells Apoptosis
por: Eftekhar-Vaghefi, Shahrzad, et al.
Publicado: (2015)

MicroRNA-101 Regulates 6-Hydroxydopamine-Induced Cell Death by Targeting Suppressor/Enhancer Lin-12-Like in SH-SY5Y Cells
por: Omura, Tomohiro, et al.
Publicado: (2021)

Comparative analysis of in vitro neurotoxicity of methylmercury, mercury, cadmium, and hydrogen peroxide on SH-SY5Y cells
por: SUDO, Kasumi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_dkclmvbd9qnan9mkpm6ir9qinq