Coupled Electrostatic and Hydrophobic Destabilisation of the Gelsolin-Actin Complex Enables Facile Detection of Ovarian Cancer Biomarker Lysophosphatidic Acid

Lysophosphatidic acid (LPA) is a promising biomarker candidate to screen for ovarian cancer (OC) and potentially stratify and treat patients according to disease stage. LPA is known to target the actin-binding protein gelsolin which is a key regulator of actin filament assembly. Previous studies hav...

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Detalles Bibliográficos
Autores principales: Davoudian, Katharina, Bhattacharya, Shayon, Thompson, Damien, Thompson, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527313/
https://www.ncbi.nlm.nih.gov/pubmed/37759826
http://dx.doi.org/10.3390/biom13091426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527313/
https://www.ncbi.nlm.nih.gov/pubmed/37759826
http://dx.doi.org/10.3390/biom13091426

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