Canagliflozin, an Inhibitor of the Na(+)-Coupled D-Glucose Cotransporter, SGLT2, Inhibits Astrocyte Swelling and Brain Swelling in Cerebral Ischemia

Brain swelling is a major cause of death and disability in ischemic stroke. Drugs of the gliflozin class, which target the Na(+)-coupled D-glucose cotransporter, SGLT2, are approved for type 2 diabetes mellitus (T2DM) and may be beneficial in other conditions, but data in cerebral ischemia are limit...

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Detalles Bibliográficos
Autores principales: Shim, Bosung, Stokum, Jesse A., Moyer, Mitchell, Tsymbalyuk, Natalya, Tsymbalyuk, Orest, Keledjian, Kaspar, Ivanova, Svetlana, Tosun, Cigdem, Gerzanich, Volodymyr, Simard, J. Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527352/
https://www.ncbi.nlm.nih.gov/pubmed/37759444
http://dx.doi.org/10.3390/cells12182221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527352/
https://www.ncbi.nlm.nih.gov/pubmed/37759444
http://dx.doi.org/10.3390/cells12182221

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