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Functional Interaction between Adenosine A(2A) and mGlu(5) Receptors Mediates STEP Phosphatase Activation and Promotes STEP/mGlu(5)R Binding in Mouse Hippocampus and Neuroblastoma Cell Line

(1) Background: Recently, we found that adenosine A(2A) receptor (A(2A)R) stimulation results in an increase in STEP phosphatase activity. In order to delve into the mechanism through which A(2A)R stimulation induced STEP activation, we investigated the involvement of mGlu(5)R since it is well docum...

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Detalles Bibliográficos
Autores principales: Mallozzi, Cinzia, Pepponi, Rita, Gaddini, Lucia, Casella, Ida, Chiodi, Valentina, Popoli, Patrizia, Domenici, Maria Rosaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527457/
https://www.ncbi.nlm.nih.gov/pubmed/37759748
http://dx.doi.org/10.3390/biom13091350