Nanoscale CAR Organization at the Immune Synapse Correlates with CAR-T Effector Functions

T cells expressing chimeric antigen receptors (CARs) are at the forefront of clinical treatment of cancers. Still, the nanoscale organization of CARs at the interface of CAR-Ts with target cells, which is essential for TCR-mediated T cell activation, remains poorly understood. Here, we studied the n...

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Detalles Bibliográficos
Autores principales: Sajman, Julia, Yakovian, Oren, Unger Deshet, Naamit, Almog, Shaked, Horn, Galit, Waks, Tova, Globerson Levin, Anat, Sherman, Eilon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527520/
https://www.ncbi.nlm.nih.gov/pubmed/37759484
http://dx.doi.org/10.3390/cells12182261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527520/
https://www.ncbi.nlm.nih.gov/pubmed/37759484
http://dx.doi.org/10.3390/cells12182261

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