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Voluntary Running Improves Behavioral and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder

Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a rare neurodevelopmental disease caused by mutations in the X-linked CDKL5 gene. CDD is characterized by a broad spectrum of clinical manifestations, including early-onset refractory epileptic seizures, intellectual disability, hyp...

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Detalles Bibliográficos
Autores principales: Mottolese, Nicola, Uguagliati, Beatrice, Tassinari, Marianna, Cerchier, Camilla Bruna, Loi, Manuela, Candini, Giulia, Rimondini, Roberto, Medici, Giorgio, Trazzi, Stefania, Ciani, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527551/
https://www.ncbi.nlm.nih.gov/pubmed/37759796
http://dx.doi.org/10.3390/biom13091396