Cargando…
Voluntary Running Improves Behavioral and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder
Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a rare neurodevelopmental disease caused by mutations in the X-linked CDKL5 gene. CDD is characterized by a broad spectrum of clinical manifestations, including early-onset refractory epileptic seizures, intellectual disability, hyp...
Autores principales: | Mottolese, Nicola, Uguagliati, Beatrice, Tassinari, Marianna, Cerchier, Camilla Bruna, Loi, Manuela, Candini, Giulia, Rimondini, Roberto, Medici, Giorgio, Trazzi, Stefania, Ciani, Elisabetta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527551/ https://www.ncbi.nlm.nih.gov/pubmed/37759796 http://dx.doi.org/10.3390/biom13091396 |
Ejemplares similares
-
Luteolin Treatment Ameliorates Brain Development and Behavioral Performance in a Mouse Model of CDKL5 Deficiency Disorder
por: Tassinari, Marianna, et al.
Publicado: (2022) -
Cardiac Functional and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder
por: Loi, Manuela, et al.
Publicado: (2023) -
Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder
por: Galvani, Giuseppe, et al.
Publicado: (2021) -
Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder
por: Loi, Manuela, et al.
Publicado: (2021) -
Expression of a Secretable, Cell-Penetrating CDKL5 Protein Enhances the Efficacy of Gene Therapy for CDKL5 Deficiency Disorder
por: Medici, Giorgio, et al.
Publicado: (2022)