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Targeted Expression to Liver of an antimiR-33 Sponge as a Gene Therapy Strategy against Hypercholesterolemia: In Vitro Study

Atherosclerosis is the leading cause of cardiovascular diseases in Mexico and worldwide. The membrane transporters ABCA1 and ABCG1 are involved in the reverse transport of cholesterol and stimulate the HDL synthesis in hepatocytes, therefore the deficiency of these transporters promotes the accelera...

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Detalles Bibliográficos
Autores principales: Montaño-Samaniego, Mariela, Sánchez-Cedillo, Jorge, Lucas-González, Amellalli, Bravo-Estupiñan, Diana M., Alarcón-Hernández, Ernesto, Rivera-Gutiérrez, Sandra, Balderas-López, José Abraham, Ibáñez-Hernández, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527677/
https://www.ncbi.nlm.nih.gov/pubmed/37754229
http://dx.doi.org/10.3390/cimb45090445