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Therapeutic Oligonucleotides: An Outlook on Chemical Strategies to Improve Endosomal Trafficking
The potential of oligonucleotide therapeutics is undeniable as more than 15 drugs have been approved to treat various diseases in the liver, central nervous system (CNS), and muscles. However, achieving effective delivery of oligonucleotide therapeutics to specific tissues still remains a major chal...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527716/ https://www.ncbi.nlm.nih.gov/pubmed/37759475 http://dx.doi.org/10.3390/cells12182253 |