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Therapeutic Oligonucleotides: An Outlook on Chemical Strategies to Improve Endosomal Trafficking

The potential of oligonucleotide therapeutics is undeniable as more than 15 drugs have been approved to treat various diseases in the liver, central nervous system (CNS), and muscles. However, achieving effective delivery of oligonucleotide therapeutics to specific tissues still remains a major chal...

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Detalles Bibliográficos
Autores principales: Mangla, Priyanka, Vicentini, Quentin, Biscans, Annabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527716/
https://www.ncbi.nlm.nih.gov/pubmed/37759475
http://dx.doi.org/10.3390/cells12182253