NAP (Davunetide): The Neuroprotective ADNP Drug Candidate Penetrates Cell Nuclei Explaining Pleiotropic Mechanisms

(1) Background: Recently, we showed aberrant nuclear/cytoplasmic boundaries/activity-dependent neuroprotective protein (ADNP) distribution in ADNP-mutated cells. This malformation was corrected upon neuronal differentiation by the ADNP-derived fragment drug candidate NAP (davunetide). Here, we inves...

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Detalles Bibliográficos
Autores principales: Ganaiem, Maram, Gildor, Nina D., Shazman, Shula, Karmon, Gidon, Ivashko-Pachima, Yanina, Gozes, Illana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527813/
https://www.ncbi.nlm.nih.gov/pubmed/37759476
http://dx.doi.org/10.3390/cells12182251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527813/
https://www.ncbi.nlm.nih.gov/pubmed/37759476
http://dx.doi.org/10.3390/cells12182251

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