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NAP (Davunetide): The Neuroprotective ADNP Drug Candidate Penetrates Cell Nuclei Explaining Pleiotropic Mechanisms
(1) Background: Recently, we showed aberrant nuclear/cytoplasmic boundaries/activity-dependent neuroprotective protein (ADNP) distribution in ADNP-mutated cells. This malformation was corrected upon neuronal differentiation by the ADNP-derived fragment drug candidate NAP (davunetide). Here, we inves...
Autores principales: | Ganaiem, Maram, Gildor, Nina D., Shazman, Shula, Karmon, Gidon, Ivashko-Pachima, Yanina, Gozes, Illana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527813/ https://www.ncbi.nlm.nih.gov/pubmed/37759476 http://dx.doi.org/10.3390/cells12182251 |
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