Mutual Modulation of the Activities of Human CYP2D6 and Four UGTs during the Metabolism of Propranolol

Cytochromes P450 (CYP) and UDP-glucuronosyltransferases (UGT) are two enzyme families that play an important role in drug metabolism, catalyzing either the functionalization or glucuronidation of xenobiotics. However, their mutual interactions are poorly understood. In this study, the functional int...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Sharma, Sangeeta Shrestha, Bureik, Matthias, Parr, Maria Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527876/
https://www.ncbi.nlm.nih.gov/pubmed/37754235
http://dx.doi.org/10.3390/cimb45090451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527876/
https://www.ncbi.nlm.nih.gov/pubmed/37754235
http://dx.doi.org/10.3390/cimb45090451

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