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Mutual Modulation of the Activities of Human CYP2D6 and Four UGTs during the Metabolism of Propranolol
Cytochromes P450 (CYP) and UDP-glucuronosyltransferases (UGT) are two enzyme families that play an important role in drug metabolism, catalyzing either the functionalization or glucuronidation of xenobiotics. However, their mutual interactions are poorly understood. In this study, the functional int...
Autores principales: | Yang, Fan, Sharma, Sangeeta Shrestha, Bureik, Matthias, Parr, Maria Kristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527876/ https://www.ncbi.nlm.nih.gov/pubmed/37754235 http://dx.doi.org/10.3390/cimb45090451 |
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