Fibrinogen γ′ promotes host survival during Staphylococcus aureus septicemia in mice

BACKGROUND: Staphylococcus aureus is a common gram-positive bacterium that is the causative agent for several human diseases, including sepsis. A key virulence mechanism is pathogen binding to host fibrinogen through the C-terminal region of the γ-chain. Previous work demonstrated that Fgg(Δ5) mice...

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Detalles Bibliográficos
Autores principales: Negrón, Oscar, Weggeman, Miranda, Grimbergen, Jos, Clark, Emily G., Abrahams, Sara, Hur, Woosuk S., Koopman, Jaap, Flick, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528022/
https://www.ncbi.nlm.nih.gov/pubmed/37001817
http://dx.doi.org/10.1016/j.jtha.2023.03.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528022/
https://www.ncbi.nlm.nih.gov/pubmed/37001817
http://dx.doi.org/10.1016/j.jtha.2023.03.019

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