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When You Come to a Fork in the Road, Take It: Wnt Signaling Activates Multiple Pathways through the APC/Axin/GSK-3 Complex

The Wnt signaling pathway is a highly conserved regulator of metazoan development and stem cell maintenance. Activation of Wnt signaling is an early step in diverse malignancies. Work over the past four decades has defined a “canonical” Wnt pathway that is initiated by Wnt proteins, secreted glycopr...

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Detalles Bibliográficos
Autores principales: Li, Chenchen, Furth, Emma E., Rustgi, Anil K., Klein, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528086/
https://www.ncbi.nlm.nih.gov/pubmed/37759479
http://dx.doi.org/10.3390/cells12182256