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Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies

Given its high biological and pharmacological activities, curcumin (CUR) offers promising applications in functional foods. However, its low stability and bioavailability have greatly hindered its application in the food industry. The present study prepared cellulose nanofiber (CNF) from bamboo shoo...

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Detalles Bibliográficos
Autores principales: Chang, Yu, Wang, Qi, Huang, Juqing, Luo, Xianliang, Huang, Yajuan, Wu, Yirui, Chen, Peng, Zheng, Yafeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528234/
https://www.ncbi.nlm.nih.gov/pubmed/37761221
http://dx.doi.org/10.3390/foods12183512
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author Chang, Yu
Wang, Qi
Huang, Juqing
Luo, Xianliang
Huang, Yajuan
Wu, Yirui
Chen, Peng
Zheng, Yafeng
author_facet Chang, Yu
Wang, Qi
Huang, Juqing
Luo, Xianliang
Huang, Yajuan
Wu, Yirui
Chen, Peng
Zheng, Yafeng
author_sort Chang, Yu
collection PubMed
description Given its high biological and pharmacological activities, curcumin (CUR) offers promising applications in functional foods. However, its low stability and bioavailability have greatly hindered its application in the food industry. The present study prepared cellulose nanofiber (CNF) from bamboo shoot processing byproducts and investigated its potential as a low-cost carrier. Our results showed that CUR was immobilized on CNF surfaces mainly through hydrogen bonding and eventually encapsulated in CNF matrices, forming a CNF–CUR complex with an encapsulation efficiency of 88.34% and a loading capacity of 67.95%. The CUR encapsulated in the complex showed improved stability after thermal and UV light treatments. Moreover, a slow and extended release pattern of CUR in a simulated gastrointestinal tract was observed, which could be appropriately described using the Korsmeyer–Peppas model. These results revealed that CNF is a promising protective carrier for the slow release of CUR, making it a better candidate for functional foods.
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spelling pubmed-105282342023-09-28 Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies Chang, Yu Wang, Qi Huang, Juqing Luo, Xianliang Huang, Yajuan Wu, Yirui Chen, Peng Zheng, Yafeng Foods Article Given its high biological and pharmacological activities, curcumin (CUR) offers promising applications in functional foods. However, its low stability and bioavailability have greatly hindered its application in the food industry. The present study prepared cellulose nanofiber (CNF) from bamboo shoot processing byproducts and investigated its potential as a low-cost carrier. Our results showed that CUR was immobilized on CNF surfaces mainly through hydrogen bonding and eventually encapsulated in CNF matrices, forming a CNF–CUR complex with an encapsulation efficiency of 88.34% and a loading capacity of 67.95%. The CUR encapsulated in the complex showed improved stability after thermal and UV light treatments. Moreover, a slow and extended release pattern of CUR in a simulated gastrointestinal tract was observed, which could be appropriately described using the Korsmeyer–Peppas model. These results revealed that CNF is a promising protective carrier for the slow release of CUR, making it a better candidate for functional foods. MDPI 2023-09-21 /pmc/articles/PMC10528234/ /pubmed/37761221 http://dx.doi.org/10.3390/foods12183512 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chang, Yu
Wang, Qi
Huang, Juqing
Luo, Xianliang
Huang, Yajuan
Wu, Yirui
Chen, Peng
Zheng, Yafeng
Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies
title Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies
title_full Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies
title_fullStr Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies
title_full_unstemmed Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies
title_short Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies
title_sort curcumin-loaded bamboo shoot cellulose nanofibers: characterization and in vitro studies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528234/
https://www.ncbi.nlm.nih.gov/pubmed/37761221
http://dx.doi.org/10.3390/foods12183512
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