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Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies
Given its high biological and pharmacological activities, curcumin (CUR) offers promising applications in functional foods. However, its low stability and bioavailability have greatly hindered its application in the food industry. The present study prepared cellulose nanofiber (CNF) from bamboo shoo...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528234/ https://www.ncbi.nlm.nih.gov/pubmed/37761221 http://dx.doi.org/10.3390/foods12183512 |
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author | Chang, Yu Wang, Qi Huang, Juqing Luo, Xianliang Huang, Yajuan Wu, Yirui Chen, Peng Zheng, Yafeng |
author_facet | Chang, Yu Wang, Qi Huang, Juqing Luo, Xianliang Huang, Yajuan Wu, Yirui Chen, Peng Zheng, Yafeng |
author_sort | Chang, Yu |
collection | PubMed |
description | Given its high biological and pharmacological activities, curcumin (CUR) offers promising applications in functional foods. However, its low stability and bioavailability have greatly hindered its application in the food industry. The present study prepared cellulose nanofiber (CNF) from bamboo shoot processing byproducts and investigated its potential as a low-cost carrier. Our results showed that CUR was immobilized on CNF surfaces mainly through hydrogen bonding and eventually encapsulated in CNF matrices, forming a CNF–CUR complex with an encapsulation efficiency of 88.34% and a loading capacity of 67.95%. The CUR encapsulated in the complex showed improved stability after thermal and UV light treatments. Moreover, a slow and extended release pattern of CUR in a simulated gastrointestinal tract was observed, which could be appropriately described using the Korsmeyer–Peppas model. These results revealed that CNF is a promising protective carrier for the slow release of CUR, making it a better candidate for functional foods. |
format | Online Article Text |
id | pubmed-10528234 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105282342023-09-28 Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies Chang, Yu Wang, Qi Huang, Juqing Luo, Xianliang Huang, Yajuan Wu, Yirui Chen, Peng Zheng, Yafeng Foods Article Given its high biological and pharmacological activities, curcumin (CUR) offers promising applications in functional foods. However, its low stability and bioavailability have greatly hindered its application in the food industry. The present study prepared cellulose nanofiber (CNF) from bamboo shoot processing byproducts and investigated its potential as a low-cost carrier. Our results showed that CUR was immobilized on CNF surfaces mainly through hydrogen bonding and eventually encapsulated in CNF matrices, forming a CNF–CUR complex with an encapsulation efficiency of 88.34% and a loading capacity of 67.95%. The CUR encapsulated in the complex showed improved stability after thermal and UV light treatments. Moreover, a slow and extended release pattern of CUR in a simulated gastrointestinal tract was observed, which could be appropriately described using the Korsmeyer–Peppas model. These results revealed that CNF is a promising protective carrier for the slow release of CUR, making it a better candidate for functional foods. MDPI 2023-09-21 /pmc/articles/PMC10528234/ /pubmed/37761221 http://dx.doi.org/10.3390/foods12183512 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Chang, Yu Wang, Qi Huang, Juqing Luo, Xianliang Huang, Yajuan Wu, Yirui Chen, Peng Zheng, Yafeng Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies |
title | Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies |
title_full | Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies |
title_fullStr | Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies |
title_full_unstemmed | Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies |
title_short | Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies |
title_sort | curcumin-loaded bamboo shoot cellulose nanofibers: characterization and in vitro studies |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528234/ https://www.ncbi.nlm.nih.gov/pubmed/37761221 http://dx.doi.org/10.3390/foods12183512 |
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