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Statins in Children with Neurofibromatosis Type 1: A Systematic Review of Randomized Controlled Trials

Background: Statins, apart from their plasma-cholesterol-lowering ability, exert several pleiotropic effects, making them a potential treatment for other diseases. Animal studies have showed that statins, through the inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase, can affect the Ras/M...

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Detalles Bibliográficos
Autores principales: Agouridis, Aris P., Palli, Nikoletta, Karagiorga, Vasiliki-Eirini, Konsoula, Afroditi, Markaki, Lamprini, Spernovasilis, Nikolaos, Tsioutis, Constantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528298/
https://www.ncbi.nlm.nih.gov/pubmed/37761518
http://dx.doi.org/10.3390/children10091556