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Statins in Children with Neurofibromatosis Type 1: A Systematic Review of Randomized Controlled Trials
Background: Statins, apart from their plasma-cholesterol-lowering ability, exert several pleiotropic effects, making them a potential treatment for other diseases. Animal studies have showed that statins, through the inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase, can affect the Ras/M...
Autores principales: | Agouridis, Aris P., Palli, Nikoletta, Karagiorga, Vasiliki-Eirini, Konsoula, Afroditi, Markaki, Lamprini, Spernovasilis, Nikolaos, Tsioutis, Constantinos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528298/ https://www.ncbi.nlm.nih.gov/pubmed/37761518 http://dx.doi.org/10.3390/children10091556 |
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