Lower female survival from an opportunistic infection reveals progesterone-driven sex bias in trained immunity

Immune responses differ between females and males, although such sex-based variance is incompletely understood. Observing that bacteremia of the opportunistic pathogen Burkholderia gladioli caused many more deaths of female than male mice bearing genetic deficiencies in adaptive immunity, we determi...

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Detalles Bibliográficos
Autores principales: Earhart, Alexander P., Karasseva, Natalia G., Storey, Kathryn M., Olthoff, Benjamin, Sarker, Md Bodruzzaman, Laffey, Kimberly G., Lange, Margaret J., Rector, R. Scott, Schulz, Laura C., Gil, Diana, Neuhauser, Claudia M., Schrum, Adam G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528383/
https://www.ncbi.nlm.nih.gov/pubmed/37590139
http://dx.doi.org/10.1016/j.celrep.2023.113007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528383/
https://www.ncbi.nlm.nih.gov/pubmed/37590139
http://dx.doi.org/10.1016/j.celrep.2023.113007

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