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Lower female survival from an opportunistic infection reveals progesterone-driven sex bias in trained immunity
Immune responses differ between females and males, although such sex-based variance is incompletely understood. Observing that bacteremia of the opportunistic pathogen Burkholderia gladioli caused many more deaths of female than male mice bearing genetic deficiencies in adaptive immunity, we determi...
Autores principales: | Earhart, Alexander P., Karasseva, Natalia G., Storey, Kathryn M., Olthoff, Benjamin, Sarker, Md Bodruzzaman, Laffey, Kimberly G., Lange, Margaret J., Rector, R. Scott, Schulz, Laura C., Gil, Diana, Neuhauser, Claudia M., Schrum, Adam G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528383/ https://www.ncbi.nlm.nih.gov/pubmed/37590139 http://dx.doi.org/10.1016/j.celrep.2023.113007 |
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