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In Silico Investigation of AKT2 Gene and Protein Abnormalities Reveals Potential Association with Insulin Resistance and Type 2 Diabetes

Type 2 diabetes (T2D) develops from insulin resistance (IR) and the dysfunction of pancreatic beta cells. The AKT2 protein is very important for the protein signaling pathway, and the non-synonymous SNP (nsSNPs) in AKT2 gene may be associated with T2D. nsSNPs can result in alterations in protein sta...

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Detalles Bibliográficos
Autores principales: Elangeeb, M. E., Elfaki, Imadeldin, Elkhalifa, M. A., Adam, Khalid M., Alameen, A. O., Elfadl, Ahmed Kamaleldin, Albalawi, Ibrahim Altedlawi, Almasoudi, Kholoud S., Almotairi, Reema, Alsaedi, Basim S. O., Alhelali, Marwan H., Mir, Mohammad Muzaffar, Amle, Dnyanesh, Mir, Rashid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528407/
https://www.ncbi.nlm.nih.gov/pubmed/37754255
http://dx.doi.org/10.3390/cimb45090471