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In Silico Investigation of AKT2 Gene and Protein Abnormalities Reveals Potential Association with Insulin Resistance and Type 2 Diabetes
Type 2 diabetes (T2D) develops from insulin resistance (IR) and the dysfunction of pancreatic beta cells. The AKT2 protein is very important for the protein signaling pathway, and the non-synonymous SNP (nsSNPs) in AKT2 gene may be associated with T2D. nsSNPs can result in alterations in protein sta...
Autores principales: | Elangeeb, M. E., Elfaki, Imadeldin, Elkhalifa, M. A., Adam, Khalid M., Alameen, A. O., Elfadl, Ahmed Kamaleldin, Albalawi, Ibrahim Altedlawi, Almasoudi, Kholoud S., Almotairi, Reema, Alsaedi, Basim S. O., Alhelali, Marwan H., Mir, Mohammad Muzaffar, Amle, Dnyanesh, Mir, Rashid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528407/ https://www.ncbi.nlm.nih.gov/pubmed/37754255 http://dx.doi.org/10.3390/cimb45090471 |
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