SREBP-1 upregulates lipophagy to maintain cholesterol homeostasis in brain tumor cells

Cholesterol is a structural component of cell membranes. How rapidly growing tumor cells maintain membrane cholesterol homeostasis is poorly understood. Here, we found that glioblastoma (GBM), the most lethal brain tumor, maintains normal levels of membrane cholesterol but with an abundant presence...

Descripción completa

Detalles Bibliográficos
Autores principales: Geng, Feng, Zhong, Yaogang, Su, Huali, Lefai, Etienne, Magaki, Shino, Cloughesy, Timothy F., Yong, William H., Chakravarti, Arnab, Guo, Deliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528745/
https://www.ncbi.nlm.nih.gov/pubmed/37436895
http://dx.doi.org/10.1016/j.celrep.2023.112790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528745/
https://www.ncbi.nlm.nih.gov/pubmed/37436895
http://dx.doi.org/10.1016/j.celrep.2023.112790

Ejemplares similares