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SREBP-1 upregulates lipophagy to maintain cholesterol homeostasis in brain tumor cells
Cholesterol is a structural component of cell membranes. How rapidly growing tumor cells maintain membrane cholesterol homeostasis is poorly understood. Here, we found that glioblastoma (GBM), the most lethal brain tumor, maintains normal levels of membrane cholesterol but with an abundant presence...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528745/ https://www.ncbi.nlm.nih.gov/pubmed/37436895 http://dx.doi.org/10.1016/j.celrep.2023.112790 |