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The synergistic ameliorative activity of peroxisome proliferator‐activated receptor‐alpha and gamma agonists, fenofibrate and pioglitazone, on hippocampal neurodegeneration in a rat model of insulin resistance

Insulin resistance (IR) is a risk factor for metabolic disorders and neurodegeneration. Peroxisome proliferator‐activated receptor (PPAR) agonists have been proven to mitigate the neuronal pathology associated with IR. However, the synergetic efficacy of these agonists is yet to be fully described....

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Detalles Bibliográficos
Autores principales: Idowu, Olumayowa K., Oluyomi, Olushola O., Faniyan, Oluwatomisin O., Dosumu, Olufunke O., Akinola, Oluwole B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528802/
https://www.ncbi.nlm.nih.gov/pubmed/37786742
http://dx.doi.org/10.1002/ibra.12059