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Lung injury induces a polarized immune response by self-antigen-specific CD4(+) Foxp3(+) regulatory T cells

Self-antigen-specific T cells are prevalent in the mature adaptive immune system but are regulated through multiple mechanisms of tolerance. However, inflammatory conditions such as tissue injury may allow these T cells to break tolerance and trigger autoimmunity. To understand how the T cell repert...

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Detalles Bibliográficos
Autores principales: Shin, Daniel S., Ratnapriya, Sneha, Cashin, Creel Ng, Kuhn, Lucy F., Rahimi, Rod A., Anthony, Robert M., Moon, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529088/
https://www.ncbi.nlm.nih.gov/pubmed/37471223
http://dx.doi.org/10.1016/j.celrep.2023.112839