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Lung injury induces a polarized immune response by self-antigen-specific CD4(+) Foxp3(+) regulatory T cells
Self-antigen-specific T cells are prevalent in the mature adaptive immune system but are regulated through multiple mechanisms of tolerance. However, inflammatory conditions such as tissue injury may allow these T cells to break tolerance and trigger autoimmunity. To understand how the T cell repert...
Autores principales: | Shin, Daniel S., Ratnapriya, Sneha, Cashin, Creel Ng, Kuhn, Lucy F., Rahimi, Rod A., Anthony, Robert M., Moon, James J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529088/ https://www.ncbi.nlm.nih.gov/pubmed/37471223 http://dx.doi.org/10.1016/j.celrep.2023.112839 |
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