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Knockdown of interleukin‐6 plays a neuroprotective role against hypoxia‐ischemia in neonatal rats via inhibition of caspase 3 and Bcl‐2‐associated X protein signaling pathway

This study aimed to investigate the role of interleukin‐6 (IL‐6) in the pathogenesis of neonatal hypoxic‐ischemic encephalopathy (NHIE). Sprague‐Dawley (SD) rats were used for the establishment of hypoxic‐ischemic (HI) model. The Zea‐Longa scoring was used to evaluate the extent of the neurological...

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Detalles Bibliográficos
Autores principales: Yang, Xiu, Liao, Ke‐Han, Deng, Isaac B., Zhang, Lan‐Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529178/
https://www.ncbi.nlm.nih.gov/pubmed/37786746
http://dx.doi.org/10.1002/ibra.12067