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ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms
The ATR kinase safeguards genomic integrity during S phase, but how ATR protects DNA replication forks remains incompletely understood. Here, we combine four distinct assays to analyze ATR functions at ongoing and newly assembled replication forks upon replication inhibition by hydroxyurea. At ongoi...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529362/ https://www.ncbi.nlm.nih.gov/pubmed/37454295 http://dx.doi.org/10.1016/j.celrep.2023.112792 |