Stromal-induced epithelial-mesenchymal transition induces targetable drug resistance in acute lymphoblastic leukemia

The bone marrow microenvironment (BME) drives drug resistance in acute lymphoblastic leukemia (ALL) through leukemic cell interactions with bone marrow (BM) niches, but the underlying mechanisms remain unclear. Here, we show that the interaction between ALL and mesenchymal stem cells (MSCs) through...

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Detalles Bibliográficos
Autores principales: Park, Chun Shik, Yoshihara, Hiroki, Gao, Qingsong, Qu, Chunxu, Iacobucci, Ilaria, Ghate, Pankaj S., Connelly, Jon P., Pruett-Miller, Shondra M., Wagner, Ben, Robinson, Camenzind G., Mishra, Ashutosh, Peng, Junmin, Yang, Lei, Rankovic, Zoran, Finkelstein, David, Luger, Selina, Litzow, Mark, Paietta, Elisabeth M., Hebbar, Nikhil, Velasquez, M. Paulina, Mullighan, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529385/
https://www.ncbi.nlm.nih.gov/pubmed/37453060
http://dx.doi.org/10.1016/j.celrep.2023.112804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529385/
https://www.ncbi.nlm.nih.gov/pubmed/37453060
http://dx.doi.org/10.1016/j.celrep.2023.112804

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