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Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification on biology
Rad24-RFC (replication factor C) loads the 9-1-1 checkpoint clamp onto the recessed 5′ ends by binding a 5′ DNA at an external surface site and threading the 3′ single-stranded DNA (ssDNA) into 9-1-1. We find here that Rad24-RFC loads 9-1-1 onto DNA gaps in preference to a recessed 5′ end, thus pres...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529453/ https://www.ncbi.nlm.nih.gov/pubmed/37392384 http://dx.doi.org/10.1016/j.celrep.2023.112694 |