The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites

The Plasmodium falciparum reticulocyte-binding protein homolog 5 (PfRH5) is the current leading blood-stage malaria vaccine candidate. PfRH5 functions as part of the pentameric PCRCR complex containing PTRAMP, CSS, PfCyRPA and PfRIPR, all of which are essential for infection of human red blood cells...

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Detalles Bibliográficos
Autores principales: Weiss, Greta E., Ragotte, Robert J., Quinkert, Doris, Lias, Amelia M., Dans, Madeline G., Boulet, Coralie, Looker, Oliver, Ventura, Olivia D., Williams, Barnabas G., Crabb, Brendan S., Draper, Simon J., Gilson, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529537/
https://www.ncbi.nlm.nih.gov/pubmed/37713419
http://dx.doi.org/10.1371/journal.ppat.1011182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529537/
https://www.ncbi.nlm.nih.gov/pubmed/37713419
http://dx.doi.org/10.1371/journal.ppat.1011182

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