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Effects of Heparan sulfate acetyl-CoA: Alpha-glucosaminide N-acetyltransferase (HGSNAT) inactivation on the structure and function of epithelial and immune cells of the testis and epididymis and sperm parameters in adult mice

Heparan sulfate (HS), an abundant component of the apical cell surface and basement membrane, belongs to the glycosaminoglycan family of carbohydrates covalently linked to proteins called heparan sulfate proteoglycans. After endocytosis, HS is degraded in the lysosome by several enzymes, including h...

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Detalles Bibliográficos
Autores principales: Carvelli, Lorena, Hermo, Louis, O’Flaherty, Cristian, Oko, Richard, Pshezhetsky, Alexey V., Morales, Carlos R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529547/
https://www.ncbi.nlm.nih.gov/pubmed/37756356
http://dx.doi.org/10.1371/journal.pone.0292157