A systematic review and meta-analysis on the efficacy of glibenclamide in animal models of intracerebral hemorrhage

Intracerebral hemorrhage (ICH) is a devastating stroke with many mechanisms of injury. Edema worsens outcome and can lead to mortality after ICH. Glibenclamide (GLC), a sulfonylurea 1- transient receptor potential melastatin 4 (Sur1-Trpm4) channel blocker, has been shown to attenuate edema in ischem...

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Detalles Bibliográficos
Autores principales: Kung, Tiffany F. C., Wilkinson, Cassandra M., Liddle, Lane J., Colbourne, Frederick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529582/
https://www.ncbi.nlm.nih.gov/pubmed/37756302
http://dx.doi.org/10.1371/journal.pone.0292033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529582/
https://www.ncbi.nlm.nih.gov/pubmed/37756302
http://dx.doi.org/10.1371/journal.pone.0292033

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