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A systematic review and meta-analysis on the efficacy of glibenclamide in animal models of intracerebral hemorrhage

Intracerebral hemorrhage (ICH) is a devastating stroke with many mechanisms of injury. Edema worsens outcome and can lead to mortality after ICH. Glibenclamide (GLC), a sulfonylurea 1- transient receptor potential melastatin 4 (Sur1-Trpm4) channel blocker, has been shown to attenuate edema in ischem...

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Detalles Bibliográficos
Autores principales:	Kung, Tiffany F. C., Wilkinson, Cassandra M., Liddle, Lane J., Colbourne, Frederick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529582/ https://www.ncbi.nlm.nih.gov/pubmed/37756302 http://dx.doi.org/10.1371/journal.pone.0292033

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