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Rescue of bmp15 deficiency in zebrafish by mutation of inha reveals mechanisms of BMP15 regulation of folliculogenesis

As an oocyte-specific growth factor, bone morphogenetic protein 15 (BMP15) plays a critical role in controlling folliculogenesis. However, the mechanism of BMP15 action remains elusive. Using zebrafish as the model, we created a bmp15 mutant using CRISPR/Cas9 and demonstrated that bmp15 deficiency c...

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Detalles Bibliográficos
Autores principales: Zhai, Yue, Zhang, Xin, Zhao, Cheng, Geng, Ruijing, Wu, Kun, Yuan, Mingzhe, Ai, Nana, Ge, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529593/
https://www.ncbi.nlm.nih.gov/pubmed/37713421
http://dx.doi.org/10.1371/journal.pgen.1010954