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Rescue of bmp15 deficiency in zebrafish by mutation of inha reveals mechanisms of BMP15 regulation of folliculogenesis
As an oocyte-specific growth factor, bone morphogenetic protein 15 (BMP15) plays a critical role in controlling folliculogenesis. However, the mechanism of BMP15 action remains elusive. Using zebrafish as the model, we created a bmp15 mutant using CRISPR/Cas9 and demonstrated that bmp15 deficiency c...
Autores principales: | Zhai, Yue, Zhang, Xin, Zhao, Cheng, Geng, Ruijing, Wu, Kun, Yuan, Mingzhe, Ai, Nana, Ge, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529593/ https://www.ncbi.nlm.nih.gov/pubmed/37713421 http://dx.doi.org/10.1371/journal.pgen.1010954 |
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